Impairment of learning, abstraction, memory, and problem-solving occur in patients with multiple sclerosis. These impairments are present in 40% of patients with multiple sclerosis in the community. Sometimes, it is an early manifestation. Mostly the impairments are seen later in the course. The impairments are mild and progress slowly. Well-practiced verbal skills are often preserved. Cognitive impairment correlates with total lesion load and degree of callosal atrophy on brain imaging. LAMP L earning A bstraction M emory P roblem-solving