Intermittent Explosive Disorder Intermittent explosive disorder (IED)  involved o utbursts of impulsive aggression with no persistent mood disruption   between the outbursts.   It requires only  3 months  for the total duration of two episodes  every week on, average.  There must have been At least three episodes with damage to property or injury to humans/animals  w ithin 12 months. It is diagnosed only if age is above 6 years.  A man with explosive outburst depicted in a painting See the ICD-11 Criteria for Intermittent explosive disorder here.  Deficits in the prefrontal cortex on MRI have been associated with impulsivity (can aid diagnosis). 1 Findings of Etiological (but not necessarily diagnostic importance): Reduced prefrontal grey matter >> antisocial personality disorder . 2 Reduced amygdala volume has been associated with a lack of empathy . Increased amygdala responses to anger stimuli > Intermittent explos...

ICD-11 Criteria for Intermittent Explosive Disorder (6C73) Intermittent explosive disorder is characterised by repeated brief episodes of verbal or physical aggression or destruction of property that represent a failure to control aggressive impulses, with the intensity of the outburst or degree of aggressiveness being grossly out of proportion to the provocation or precipitating psychosocial stressors. The symptoms are not better explained by another mental, behavioural, or neurodevelopmental disorder and are not part of a pattern of chronic anger and irritability (e.g., in oppositional defiant disorder). The behaviour pattern is of sufficient severity to result in significant impairment in personal, family, social, educational, occupational or other important areas of functioning. Exclusions:               Oppositional defiant disorder (6C90)   6C7Y      Other specified impulse control disorders...