Opiate Withdrawal History and Physical Examination Opiate withdrawal symptoms peak between 36-72 hours. Symptoms run their course in 5-7 days, though craving continues for some time. Withdrawal from Heroin Withdrawal from heroin may begin up to 8 hours after the last use. During the next few hours, the person experiences muscle pain, sneezing, sweating; tearfulness; yawning excessively. At 36 hours after the last use, symptoms are most severe. These symptoms include chills, muscle cramps, flushing, sweating, tachycardia, hypertension, inability to sleep, vomiting & diarrhoea . Symptoms typically continue for about 72 hours & gradually diminish over 5-10 days. History This history part is in Urdu/Hindi. I will add the " Objective Opiate Withdrawal Scale" soon here so anyone can benefit. For now: COWS Aap kia istemal karty Akhri bar kab lia hai aap ne Abhi dil chahta ke aap dobara se kar lyn? Kitna had tak? Gutno ya baqi jorho...