Cognitive Deficits in Multiple Sclerosis

Impairment of learning, abstraction, memory, and problem-solving occur in patients with multiple sclerosis. These impairments are present in 40% of patients with multiple sclerosis in the community. Sometimes, it is an early manifestation.

Mostly the impairments are seen later in the course.
The impairments are mild and progress slowly.
Well-practiced verbal skills are often preserved.

Cognitive impairment correlates with total lesion load and degree of callosal atrophy on brain imaging.

LAMP

Learning
Abstraction
Memory
Problem-solving

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